Associate Director, Pharmacometrics

Title: Associate Director, Pharmacometrics

Location: United States (Fully Remote)

Job Type: Full-Time

About the Role: The Pharmacometrics leader will be responsible for the design and implementation of quantitative, data-driven modeling and simulation strategies to inform decision-making across all phases of drug development, from early development through late-stage clinical trials. You will lead PK/PD modeling and simulation efforts across a range of therapeutic areas.

Skills and Qualifications:

• Education: M.S. or PhD in Mathematics, Statistics, Pharmacometrics, Pharmacokinetics (Or related field) preferred.
• Experience: 4+ years of PKPD Modeling and Simulation Experience
• Scriptable modeling and simulation language (e.g. R, MatLab, Python) experience
• Expertise with domain-specific modeling software (e.g. NONMEM, ADAPT, Monolix) and Bayesian modeling software (e.g. Stan, JAGS, OpenBUGS)

Key Responsibilities:

• Develop population pharmacokinetic (PK), pharmacodynamic (PD), exposure-response, disease progression, and/or systems pharmacology models
• Apply models to support decision-making through Monte-Carlo simulation
• Perform model-based meta-analysis of therapeutic area summary-level data
• Perform quality control of modeling and simulation analyses
• Develop and execute modeling and simulation strategies