SRA- Antibody Discovery (Phage Display)
Job Title: Senior Research Associate - Antibody Discovery
Position Summary:
Out client is seeking a highly motivated Senior Research Associate to join our antibody discovery team, with a strong emphasis on phage display technology. This role is critical to the development of therapeutic and diagnostic antibodies and will involve executing a broad range of lab-based techniques including phage display library screening, antibody production, and downstream characterization.
Key Responsibilities:
Lead and support high-throughput screening of antibody libraries using phage display platforms.
Design and execute experiments to isolate and optimize antibody candidates via phage display selection campaigns.
Perform binding and functional assays (e.g., ELISA, flow cytometry, SPR, BLI) to assess antibody-antigen interactions.
Express and purify antibodies using molecular biology and protein production workflows (e.g., PCR, cloning, transient/stable transfection, chromatography).
Analyze experimental data, draw conclusions, and communicate findings in team settings.
Maintain thorough, well-organized laboratory records and documentation of protocols and results.
Contribute to the development of reports, presentations, and potential scientific publications.
Collaborate with cross-functional team members and external partners to drive project milestones.
Qualifications:
Bachelor's degree in Molecular Biology, Biochemistry, Immunology, or a related scientific field is required.
Master's degree preferred.
Minimum of two years of hands-on laboratory experience in antibody discovery, ideally with direct phage display experience.
Industry experience is a plus.
Skills and Competencies:
Deep understanding of phage display techniques and antibody library screening methodologies.
Proficiency in molecular biology techniques such as cloning, PCR, and site-directed mutagenesis.
Practical experience with antibody characterization assays (e.g., ELISA, flow cytometry, SPR, BLI).
Familiarity with protein expression and purification in mammalian, bacterial, or yeast systems.
Strong analytical thinking and problem-solving abilities.
Excellent organizational and time management skills; able to balance multiple priorities.
Effective communication skills, both written and verbal.
Self-starter with a collaborative approach and the ability to work independently.
Skilled in data analysis tools such as MS Excel; experience with GraphPad Prism and SharePoint is a plus.
Basic understanding of statistics relevant to experimental data interpretation.
Work Environment:
Laboratory-based position involving chemical reagents and Biosafety Level 2 materials.
May include handling of human blood and/or blood products under BSL-2 conditions.