Executive Director, Clinical Development (Autoimmune)

Job Type: Full Time

Salary: 200K - 300K

Location: Alameda, CA (3-4 days a week onsite)

Company Summary:

Our client is a global clinical-stage biotechnology company pioneering cell therapies to treat cancer and autoimmune diseases. Founded in 2017, they leverage ACC technology to arm T cells with tumor targeting antibodies. Their platform incorporates click chemistry, a Nobel Prize-winning technology known to increase precision and efficiency.

About the role:

As the Executive Director, Clinical Development in a small, agile team, you will work directly with the CEO and executive leadership to drive early development strategy and execution for our lead allogeneic gamma delta T cell therapy. You'll have the chance to build and lead a nimble team while playing an active, hands-on role in protocol development, trial execution, data analysis, and regulatory planning.

Key Responsibilities:

• Strategic Leadership
• Define and lead overall clinical development strategy
• Prioritize indications based on scientific rationale, unmet medical need, and regulatory and commercial feasibility
• Serve as a core member of the executive team, including portfolio and program level decision-making
• Clinical Development
• Design and oversee Ph 1/2 pivotal trials
• Lead protocol development, data review, and interpretation to inform clinical decision making
• Collaborate with investigators and KOLs to expand clinical applications and evidence generation
• Regulatory & Medical Strategy
• Lead regulatory interactions and engage with global health authorities to support clinical programs
• Team Building & Cross- Functional Coordination
• Build and lead a high performing clinical development team
• Key individual contributor during early stages while scaling the function
• Represent the autoimmune development strategy internally and externally

Requirements:

• MD, MD/PhD, or PharmD
• 10+ years of clinical development experience - MUST HAVE PHASE I/II
• 3+ years of experience at Senior Director level or currently, an Executive Director
• Proven success in building and leading clinical function at a small biotech
• Background in cell therapy, monoclobal antibodies, or B cell targeted agents is preferred.
• Mandarin proficiency is a plus.
• Willingness to travel internationally.

Benefits:

• Pre-IPO (US) equity
• Competitive benefits package and 401K matching
• Opportunity to build and lead a clinical group from group up at an organization with promising science and an innovative team.