Senior Scientist - Assay Development
Position Overview
We are seeking a Senior Scientist, Assay Development to lead the cfDNA workflow upstream of the electrochemical readout. This individual will be responsible for protocol development, pre-analytical QC, and clinical validation execution, including ownership of an upcoming pilot study.
This is a hands-on, individual contributor role focused on execution and scientific rigor rather than team management. The hire will play a central role in a mission-critical validation effort, bringing prior experience running clinical studies and ensuring the robustness of assay performance.
Key Responsibilities
- Lead the end-to-end cfDNA workflow, including:
- Sample handling and plasma processing
- cfDNA extraction and preparation
- Pre-analytical quality control and assay optimization
- Own execution of a clinical pilot study
- Design, refine, and troubleshoot protocols to improve assay reproducibility and performance
- Identify and mitigate points of failure within liquid biopsy workflows
- Contribute to clinical validation strategy and execution
- Generate high-quality data and support external review of results
- Collaborate closely with cross-functional teams across platform development
Required Qualifications
- 5+ years of industry experience in cfDNA or liquid biopsy
- Prior experience at leading liquid biopsy or diagnostics-focused organizations (e.g., early cancer detection or NGS-based testing platforms)
- Demonstrated experience leading clinical pilots
- Strong understanding of liquid biopsy workflows and failure modes
- Experience with clinical validation in a regulated environment (CLIA/CAP)
- Proven ability to execute hands-on wet lab work in a fast-paced environment
Preferred Qualifications
- PhD in molecular biology, bioengineering, or related field (strongly preferred)
- Experience working in early-stage or R&D-heavy environments
- Track record of building or refining assay workflows for clinical use
If this sounds like a potential fit for you, please send in your application!
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