Research Scientist
Position Overview
A highly motivated and detail‑oriented Research Scientist is sought to support an expanding aging and retinal assay platform. This role centers on elucidating mechanisms of aging and retinal degeneration and contributes to a broader portfolio of neurodegenerative disease initiatives.
Working under the guidance of the Principal Investigator, you will lead key experimental workflows and assay pipelines using rodent models and ex vivo tissues. The position requires generating high‑quality molecular, cellular, and imaging data to inform therapeutic discovery. It is well suited for a scientist who excels in hands‑on translational research and in developing robust, reproducible assays that can be leveraged across multiple projects.
About the Organization
The organization is a biotechnology enterprise focused on creating innovative therapies for complex neurodegenerative and age‑associated disorders. Its work integrates decades of scientific research with a forward‑looking strategy that combines proprietary bioactive compounds and AI‑driven insights derived from disease‑specific data.
Qualifications
Required
- Ph.D. in Neuroscience, Biology, Pharmacology, or a related discipline
- At least 1 year of applied research experience in the biotech or pharmaceutical industry
- Solid foundation in molecular and cellular biology
- Hands-on experience with rodent models and tissue‑based workflows, particularly ocular/retinal tissues
- Proficiency in immunohistochemistry, confocal microscopy, PCR/qPCR, and Western blotting
- Strong quantitative and statistical analysis competencies
- Experience designing experiments, interpreting data, and maintaining detailed laboratory documentation
- Ability to troubleshoot and independently follow complex research protocols
- Excellent communication skills-written, oral, and interpersonal
- High attention to detail and outstanding organizational abilities
- Strong commitment to laboratory safety and compliance
Preferred / Nice to Have
- Direct experience with retinal degeneration, ocular disease models, or visual system neuroscience
- Background in aging biology, geroscience, or age‑related tissue changes in rodents
- Demonstrated track record in assay development, optimization, SOP creation, or platform building
- Basic bioinformatics capabilities
- Familiarity with AI‑enabled approaches in biomedical research
Key Responsibilities
Retinal & Aging Assays
- Lead the development, optimization, and validation of retinal and aging‑related molecular and cellular assays supporting multiple internal research programs
- Oversee retinal tissue workflows, including eye dissection, retinal isolation, sectioning (cryostat or vibratome), staining, and quantitative degeneration scoring
- Establish SOPs, QC parameters, and documentation to ensure assay reproducibility and scalability
- Integrate molecular and imaging data into cohesive datasets for studying aging and retinal disease mechanisms
In Vivo & Ex Vivo Experimental Execution
- Conduct studies in accordance with approved protocols
- Perform rodent handling, dosing, and tissue collection for retinal degeneration and aging studies-including harvesting eyes and age‑related brain regions
- Execute assays in live or freshly isolated tissues (retina, optic nerve, CNS) to evaluate therapeutic responses and aging biomarkers
- Perform immunohistochemical staining, confocal imaging, and analysis with endpoints focused on retinal and aging metrics
Data Generation, Analysis & Reporting
- Analyze, interpret, and rigorously summarize experimental findings
- Maintain accurate laboratory records, metadata, and organized datasets
- Help collect, enter, and analyze multi‑assay data streams supporting retinal and aging programs
- Contribute to research reports, presentations, grant materials, investor communications, and manuscripts
Program Support & Lab Operations
- Support mouse colony management relevant to retinal and aging work (breeding coordination, genotyping oversight as needed)
- Conduct literature searches and help integrate findings to shape ongoing research strategy
- Participate in team meetings and provide regular updates to the Principal Investigator
- Collaborate cross‑functionally across scientific teams
- Maintain a clean, safe, and well‑organized laboratory environment and complete all required safety training
- Perform other research‑related tasks as needed
FAQs
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