Scientist, IVG/IVF
Scientist, In Vitro Gametogenesis/IVF
Experience Level: PhD or equivalent experience
About the Organization
A biotech who is advancing the field of reproductive biology by developing functional human oocytes derived from induced pluripotent stem cells (iPSCs). Its mission is to expand possibilities in fertility, reproductive health, and genetic diversity. The long‑term vision includes enabling later‑age parenthood, improving genetic screening of eggs, and potentially supporting same‑sex reproduction through innovative cellular technologies.
The team integrates expertise across stem cell science, developmental biology, and synthetic biology to drive transformative progress in the field.
The Role
We are looking for a highly skilled, driven, and collaborative Scientist to join our research group. This position involves extensive hands‑on cell culture work, experimental design, protocol development, and data analysis.
The Scientist will work primarily with mouse pluripotent stem cell lines (ESCs and iPSCs) to refine and expand in vitro gametogenesis methodologies, generating robust datasets that help guide translation into human systems. The ideal candidate brings strong technical depth in stem cell culture and solid conceptual understanding of developmental pathways and cell fate transitions.
Responsibilities
- Develop, refine, and implement protocols for generating mouse iPSC lines
- Culture, differentiate, and genetically engineer mouse ESC and iPSC lines, including CRISPR-based approaches
- Optimize and standardize differentiation workflows to produce gonadal cell types from pluripotent stem cells
- Lead experimental planning, troubleshooting, and method development for in vitro gametogenesis projects
- Analyze experimental data, share results with the broader team, and support cross-team process improvements
- Maintain clear, organized, and thorough experimental documentation and data records
Qualifications
- Demonstrated expertise in pluripotent stem cell culture and differentiation; mouse experience preferred (human acceptable)
- Strong grounding in developmental biology and stem cell biology, ideally within mouse systems
- Ability to interpret and discuss sequencing datasets (e.g., 10x scRNA-seq, Smart‑seq2)
- Experience in one or more of the following is strongly preferred:
- Immunofluorescence imaging
- FACS-based cell sorting
- Understanding of epigenetic mechanisms and developmental transitions
- Proven ability to execute complex experiments with rigor and attention to detail
- Strong communication, collaboration, and organizational skills
- Mission-driven attitude and enthusiasm for impactful scientific advancement
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