Sr. Director, Clinical Pharmacologist


USA
Permanent
Negotiable
Pharmacology
PR/548351_1750290472
Sr. Director, Clinical Pharmacologist

Senior Director, Clinical Pharmacology

📍 Remote | Full-Time | Executive Level

Are you a seasoned clinical pharmacologist with a passion for advancing innovative therapies in neuroscience and sleep medicine? We are partnering with a cutting-edge biopharmaceutical company that is redefining R&D through a data-driven, asset-centric model. This organization is committed to accelerating the development of high-conviction programs with strong biological validation.

We are seeking a Senior Director, Clinical Pharmacology to lead translational pharmacokinetic and pharmacodynamic strategies within CNS. This is a high-impact role with broad visibility across clinical development, regulatory strategy, and cross-functional collaboration.


Key Responsibilities

  • Lead clinical pharmacology strategy and execution for multiple programs in CNS disorders.
  • Design and oversee clinical pharmacology studies in collaboration with internal teams, external partners, and key opinion leaders.
  • Apply PK/PD modeling and simulation to support dose selection, efficacy, and safety assessments.
  • Manage vendors and ensure high-quality pharmacokinetic data collection and analysis.
  • Draft and review clinical protocols, study reports, and regulatory documents (INDs, NDAs).
  • Present findings to internal stakeholders and contribute to scientific publications and conferences.
  • Collaborate cross-functionally with nonclinical, clinical, regulatory, and CMC teams.

Qualifications

  • PhD or equivalent in pharmacokinetics, pharmacology, pharmaceutical sciences, or related field.
  • 10+ years of industry experience in clinical pharmacology, with a focus on small molecules.
  • Proven leadership in clinical pharmacology strategy and regulatory submissions.
  • Hands-on experience with PK/PD modeling tools (e.g., NONMEM, Phoenix, R, SAS).
  • Experience in CNS drug development is highly desirable.
  • Strong communication skills and ability to influence in a matrixed environment.
  • Familiarity with US and EU regulatory guidelines.

Why Join?

  • Work with a nimble, science-first organization that values speed, data, and innovation.
  • Contribute to programs with strong biological rationale and high potential for impact.
  • Enjoy flexibility with a remote-first work environment and global collaboration.

🔍 Interested in learning more?
Apply now or reach out confidentially to discuss how this opportunity aligns with your career goals.

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