Director of Clinical Operations
Director of Clinical Operations
Location: Boston, MA
Salary: $190,000-$250,000 (USD) + Performance Bonus + Pre-IPO Equity
Company Summary:
Join a next-generation biotech at the intersection of AI and endocrinology. This Boston-based company is reimagining how we discover and develop therapies for complex hormonal and metabolic disorders. With a proprietary platform that integrates machine learning, medicinal chemistry, and translational biology, the team is advancing a pipeline of novel small molecules targeting endocrine pathways with high unmet need. As they prepare to enter the clinic, you'll be the operational force behind their first-in-human trials-building systems, leading execution, and shaping the future of endocrine care.
What You'll Do:
- Own clinical operations strategy and execution for endocrine programs, including rare and chronic metabolic diseases. Drive trials from IND through Phase 2/3 with precision and urgency.
- Establish SOPs, select and manage CROs, and implement scalable systems that support rapid trial startup and data integrity.
- Leverage digital tools, AI-enabled trial design, and real-world data to optimize patient recruitment, site selection, and endpoint measurement.
- Collaborate with computational chemists, translational scientists, and regulatory experts to ensure trials are scientifically aligned and operationally sound.
- Hire, mentor, and inspire a nimble clinical operations group that thrives in a fast-paced, high-accountability environment.
What You Bring:
- Advanced degree in life sciences or healthcare preferred, with a strong understanding of endocrine biology and clinical development.
- 10+ years in clinical operations, including leadership roles in biotech. Experience with small molecule programs and endocrine/metabolic indications is highly desirable.
- Proven track record of IND submissions and global trial execution, with deep knowledge of FDA, EMA, and ICH guidelines.
If you or someone you know thrives in ambiguity, love building from scratch, and bring a hands-on, solutions-first approach to every challenge, we'd love to speak with you.