Contract, Drug Metabolism and Pharmacokinetics (DMPK)

A leading biopharmaceutical organisation is seeking an experienced Contract Scientist - Drug Metabolism & Pharmacokinetics (DMPK) to support discovery and early development programmes. This role is suited to candidates with stronghands‑on laboratory experience and a solid background in conductingDMPK studies.

Please note: demonstrated, practical DMPK experience is essential. Applicants without direct DMPK laboratory experience cannot be considered.

Key Responsibilities

• Conducting established in vitro and in vivo metabolism and bioanalysis assays
• Operating, troubleshooting, and maintaining LC‑MS/MS systems
• Supporting the development and optimisation of DMPK assays
• Analysing, interpreting, and documenting experimental data for internal project teams
• Recording study details in laboratory systems and preparing technical reports
• Ensuring adherence to safety guidelines, regulatory requirements, and internal SOPs
• Contributing to general laboratory operations, including equipment maintenance and capital equipment planning

Required Experience & Qualifications

• MSc in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or related discipline with 2+ years of relevant experience,
  OR
• BSc in the same fields with 4+ years of relevant industry experience

Essential Technical Expertise

• Proven experience inDMPK assays, including:
  • Metabolic stability in microsomes and hepatocytes
  • CYP inhibition and induction assays
  • Bioanalysis in various biological matrices
• Hands‑on experience with LC‑MS instruments and automated liquid handling systems
• Strong understanding of DMPK principles and laboratory methodologies

Additional Skills

• Excellent analytical, problem‑solving, and organisational abilities
• Strong written and verbal communication skills
• Ability to manage multiple projects in a fast‑paced, matrixed environment
• Proficiency with Microsoft Office
• Ability to work both independently and collaboratively