Principal Investigator

Principal Investigator -Clinical Research

Springfield, Missouri

Relocation Assistance Available

Full-Time | On-Site

About the Opportunity

An established clinical research organization is seeking a Principal Investigator to provide medical leadership across a diverse portfolio of clinical trials.

This position offers the opportunity to remain actively involved in patient care and clinical research while working within a highly supported environment featuring experienced research staff, dedicated recruitment resources, established infrastructure, and strong sponsor relationships.

The successful candidate will oversee clinical trials, ensure participant safety, maintain protocol compliance, and collaborate closely with research teams and sponsors to deliver high-quality studies.

Why Consider This Opportunity?

• Established clinical research program with decades of experience
• Significant infrastructure already in place, allowing physicians to focus on clinical oversight and research execution
• Broad exposure to Phase I-IV clinical trials
• Opportunity to mentor research staff and support other investigators
• High level of autonomy and physician leadership
• Collaboration with leading pharmaceutical and biotechnology sponsors
• Strong long-term career growth potential
• Relocation support available for qualified candidates

Key Responsibilities

• Serve as Principal Investigator for early phase industry-sponsored clinical trials
• Ensure studies are conducted in accordance with ICH-GCP guidelines and protocol requirements
• Oversee participant safety, informed consent, and study conduct
• Review eligibility criteria and perform medical assessments
• Evaluate adverse events and ongoing participant safety
• Collaborate with sponsors, IRBs, monitors, and auditors
• Provide leadership and mentorship to clinical research staff
• Support overall study quality, regulatory compliance, and data integrity

Qualifications

• MD or DO
• Board Certified preferred but not required
• Previous experience as a Principal Investigator or Sub-Investigator preferred
• Strong knowledge of ICH-GCP and clinical research regulations
• Experience in Endocrinology, Diabetes, Obesity, Metabolic Disease, Thyroid Disease, Internal Medicine, or related therapeutic areas preferred

If you are interested in learning more about this opportunity, please apply directly for a confidential discussion.