Contract, Drug Metabolism and Pharmacokinetics (DMPK)
Contract DMPK Scientist
Please note: demonstrated, practical DMPK experience is essential. Applicants without direct DMPK laboratory experience cannot be considered.
Key Responsibilities
- Conducting established in vitro and in vivo metabolism and bioanalysis assays
- Operating, troubleshooting, and maintaining LC‑MS/MS systems
- Supporting the development and optimisation of DMPK assays
- Analysing, interpreting, and documenting experimental data for internal project teams
- Recording study details in laboratory systems and preparing technical reports
- Ensuring adherence to safety guidelines, regulatory requirements, and internal SOPs
- Contributing to general laboratory operations, including equipment maintenance and capital equipment planning
Required Experience & Qualifications
- MSc in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or related discipline with 2+ years of relevant experience,
OR - BSc in the same fields with 4+ years of relevant industry experience
Essential Technical Expertise
- Proven experience inDMPK assays, including:
- Metabolic stability in microsomes and hepatocytes
- CYP inhibition and induction assays
- Bioanalysis in various biological matrices
- Hands‑on experience with LC‑MS instruments and automated liquid handling systems
- Strong understanding of DMPK principles and laboratory methodologies
Additional Skills
- Excellent analytical, problem‑solving, and organisational abilities
- Strong written and verbal communication skills
- Ability to manage multiple projects in a fast‑paced, matrixed environment
- Proficiency with Microsoft Office
- Ability to work both independently and collaboratively
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