Senior Vice President, Clinical Operations

Job Title: Senior Vice President, Clinical Operations

Location: New York

Reports To: Head of Clinical Operations

Total Compensation: $1.8M+ (Base + Bonus + Equity)

About the Company

This is a leading global pharmaceutical organization focused on discovering, developing, and delivering innovative medicines for serious diseases. The company integrates cutting-edge science with large-scale manufacturing capabilities and a robust pipeline spanning multiple therapeutic areas, including oncology, immunology, ophthalmology, cardiovascular, and rare diseases. Known for pioneering biologics and genetic-based therapies, the organization emphasizes translational research, precision medicine, and patient-centric solutions.

Position Overview

The SVP of Clinical Operations will lead global clinical trial execution across all phases, ensuring operational excellence, compliance, and strategic alignment with corporate objectives. This role is pivotal in driving the success of late-stage programs and accelerating timelines for innovative therapies.

Key Responsibilities

• Strategic Leadership:
• Define and execute the global clinical operations strategy across multiple therapeutic areas.
• Partner with R&D, Regulatory, and Commercial teams to align operational plans with corporate goals.
• Operational Excellence:
• Oversee planning, initiation, and execution of Phase I-IV clinical trials, including pivotal studies.
• Ensure adherence to GCP, ICH guidelines, and regulatory requirements globally.
• Team Development:
• Lead and mentor a high-performing global clinical operations organization (hundreds of FTEs).
• Drive a culture of accountability, innovation, and continuous improvement.
• Vendor & Budget Oversight:
• Manage strategic partnerships with CROs and technology vendors.
• Oversee clinical operations budgets exceeding $500M annually.
• Governance & Risk Management:
• Establish governance frameworks for trial oversight, risk mitigation, and quality assurance.
• Represent Clinical Operations in executive leadership forums and external stakeholder meetings.

Qualifications

• Advanced degree (MD, PharmD, PhD, or equivalent strongly preferred).
• 15+ years of experience in clinical operations leadership within biopharma.
• Proven track record of delivering global Phase III programs and regulatory submissions.
• Expertise in operational strategy, resource planning, and vendor management.
• Exceptional leadership, communication, and cross-functional collaboration skills.

Compensation & Benefits

• Competitive base salary.
• Annual performance bonus.
• Significant long-term equity incentives.
• Comprehensive health and retirement benefits.