I am currently working with a small, pre-clinical stage biotech company based in the San Francisco Bay Area who are in search of a Scientist to join their team.
You will support early drug discovery efforts in oncology, immuno-oncology (IO) and inflammation.
Your responsibilities will include but not limited to:
- Execution and analysis of in vitro cellular assays to support small molecule discovery efforts as well as new target identification and understanding of mechanisms of action.
- You will work closely with scientists within the group and present their findings to the department and project teams.
- Strong scientific curiosity and initiative; hands-on and resourceful
Qualifications will include but not limited to:
- Ph.D. in cell biology, immunology or related field (Bachelor's or Master's degree with industry experience)
- Hands-on experience in the development, optimization and execution of cellular assays applying multiple techniques including primary cell isolation, tissue culture, ELISA, flow cytometry, Western and multiplexing technologies (e.g. Luminex, MesoScale)
- Demonstrated track record in functional assay development in oncology and/or immunology
- Familiarity with primary cell tissue culture, molecular biology techniques, CRISPR engineering of cells and the use of siRNA/shRNA knockdown techniques to support mechanism of action studies for drug candidates and target identification
- Ability to conceive, design and execute hypothesis-testing experiments that directly contribute to project success is essential
- Detail oriented with excellent communication and presentation skills
- Background in cancer cell biology required with previous experience in the ubiquitin-proteasome (UPS) system a plus!
If interested, please do not hesitate to apply now!